Rubella or German Measles is caused by the rubella virus. It is different from measles in that it primarily affects the skin and lymph nodes. In rare cases, rubella can lead to arthritis, encephalitis, myocarditis and thrombocytopenia. Rubella or German measles can have serious repercussions on a pregnant woman since it affect the developing fetus. It can lead to growth and mental retardation as well as malformation of the eyes and heart.
Rubella manifests in symptoms such as fever and swollen tender lymph nodes. There is rash that appears all over the body. The rashes are light pink patches that last about 3 days. A patient suffering from rubella suffers headache, loss of appetite and runny nose. There might be mild conjunctivitis. Often pain and swelling is noticed in the joints.
A virus culture helps in detecting the type of rubella antibodies in the blood. Paracetamol or ibuprofen can reduce pain and fever. Rubella is usually self-limiting and lasts for about 2- 3 weeks. There is no treatment for this disease. Rubella vaccine is part of the MMR immunization scheduled for children. A second dose is recommended again around 4 - 6 years.
CK blood test
A Creatinine Kinase test is a blood test that measures the levels of Creatinine phosphokinase (CPK). It is an enzyme found predominantly in the heart tissue, brain and skeletal muscle. The CK blood test is commonly used to diagnose the existence of heart muscle damage. The CK blood test result shows an increase above normal in a person's blood test about six hours after the start of a heart attack.
It reaches its peak in about 18 hours and returns to normal in 24 to 36 hours. When the total CPK level is substantially elevated, then it is indicative of injury or stress to heart, brain or skeletal areas. The small amount of CPK that is normally in the blood comes from the muscles. The CPK blood test also helps in cost-effective management of people with suspected coronary atherosclerosis. It also evaluates the extent of muscle damage caused by drugs, trauma or immobility.
Abnormal CK-MB (one of three CK isoenzymes) or troponin levels are associated with Myocyte Necrosis and the diagnosis of Myocardial infarction. The Cardiac Markers of Cardiac Myocyte Necrosis (damage to the Cardiac muscle cells), myoglobin, CK, CK-MB and troponin I and T are primarily used to identify acute Myocardial Infarction.
It is used in early detection of dermatomyositis and polymyositis. It is also used to distinguish malignant hyperthermia from a post operative infection. It helps to discover carriers of muscular dystrophy.
The normal range for Creatinine Kinase (CK or CPK) blood test:
Male: 38 - 174 units/L
Female: 96 - 140 units/L
Increased levels of CK also can be found in viral myositis and hypothyroidism. Higher than normal CPK levels is indicative of the following conditions:
Serum CKMB levels are tested to check for myocardial injury. It is another important cardiac marker. The primary source of CKMB is myocardium although it is also found in skeletal muscle. Typically CKMB tests have now been replaced by Troponin test. But in cases of abnormal Troponin assay results or suspected re-infarction in the hospital, the CKMB serum test is still used.
High levels of CK MB are noticed in cases of polymyositis and rhabdomyolysis. Patients suffering pulmonary embolism, hypothyroidism, and muscular dystrophy or carbon monoxide poisoning can also show higher levels of serum CKMB. The reference range is about 56.2 pg/mL.
An electrocardiogram or ECG is a non-invasive diagnostic test to record the electrical voltage in the heart so as to understand its functioning and regularity of heart beats. The electrocardiogram or EKG can help in diagnosing cardiovascular disease. The ECG is used to check for any damage to the heart and regulate the functioning of the pacemaker.
An electrocardiogram measures the electrical activity within the heart, thereby throwing light on the how the heart muscles function. This test is not painful. An ECG is recommended for patients who complain of regular chest pain or palpitations to check for the normal functioning of the heart. It can help in detecting heart attack or (ischaemia) ischemia. If a patient suffers from hypothermia, pulmonary embolism, mitral stenosis or left ventricular hypertrophy, an EKG can help in diagnosis.
Other non-cardiac problems such as drug overdose or electrolyte imbalance can be diagnosed with an EKG. Abnormal results from an ECG test may be indicative of arrhythmia, myocarditis, impending heart attack or enlarged heart.
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Bibliography / Reference
Collection of Pages - Last revised Date: October 21, 2019