Rheumatologist is a specialist who specializes in the diagnosis and treatment of arthritis and diseases of the joint, bones, and muscles. Rheumatologists complete medical school, complete another three years training in internal medicine and thereafter complete another three years in rheumatology training.
Modern techniques in the field of rheumatology
Treatment for rheumatology has seen a drastic change for the past few years, modern techniques used in the field of rheumatology include
Turkish dermatologist, Hulusi Behcet (1889-1948) recognized and reported in 1937 symptoms of Behcet's syndrome. A dental infection is attributed as the etiology of the disease. The American Behcet's Disease Foundation (ABDA) was founded in 1978 with the objective to provide support to patients and family as well the caregivers. In the absence of a cure or a single test to definitely determine Behcet's syndrome or Behcet's disease, educate about the syndrome to seek prompt medical attention for treatment.
Morbus Behcet or Silk Road disease is the other name for Behcet Syndrome or disease. Month of May is Behcet's Awareness month and May 20th is Behcet's awareness day. The focus is on spreading awareness and stress the importance of self-help.
Behcet's syndrome facts
Behcet's syndrome – Autoimmune disease
There are over 14, 000 auto-immune diseases and 7000 plus are rare. Behcet's syndrome is rare. Autoimmune disease occurs when the body's immune system mistakenly attacks its own healthy tissues. Though the clinical feature of auto immunity is absent, Behcet's syndrome is classified as an autoimmune disease as it has various aspects related to autoimmune disease. Enhanced inflammatory response (inflammation of blood vessels) is one such aspect. Significant number of women as compared to men are more likely to be affected by autoimmune disease. Estrogen predisposes women to autoimmune disease.
Behcet's syndrome symptoms
The inflammation of blood vessels, particularly veins causes symptoms in many parts of the body. Swelling, redness, heat and pain are select features of an inflammation. Though Behcet's disease can affect any part of the body, involvement of the neurological system is known as neuro-Behcet's disease and is rated the most disabling complication of the disease. Not that common, neuro-Behcet's disease affects about 10 per cent of people with Behcet's disease.
The most common symptom of Behcet's syndrome is the regular occurrence of ulcers in the mouth and genitals. The symptoms are an off-shoot of inflammation of the eyes, skin, arteries, veins, joints, nervous and digestive systems and heart. Symptoms can be mild or severe. Symptoms can be noticed between ages 20-30 years.
Mouth ulcers: May look like normal mouth ulcers but are more painful and numerous in number. Ulcers develop in the tongue, lips, and gums and inside of the cheeks. Even if the ulcers heal within a couple of weeks, they recur.
Genital ulcers: In men, though genital ulcers can appear anywhere in the groin area, including the penis, it is more common on the scrotum. In women, the ulcers appear on the cervix (neck of the womb), vulva or vagina. The ulcers are usually painful and scars appear around the area.
Skin lesions: Resembling acne, pustular skin lesions can appear anywhere on the body. Erythema nodosum results in red, painful, tender lumps that can measure one to five centimeters. It is the result of inflammation in the fatty layer of the skin. It can appear on the legs and ankles but can also appear on the face, neck or arms. Erythema nodosum related to other disease heal without scars but if related to Behcet's disease, leaves the skin totally discolored.
Inflammation of the eyes: Sudden inflammation of the eyes is a common symptom of Behcet's syndrome. A group of connected tissues, uveal tract is inside the eye. This uveal tract gets inflamed. Uveitis as it is named can cause symptoms such as, painful red eyes, blurred vision and floaters (dots that move across the field of vision). With a possibility of permanent visual impairment, it is best to seek medical attention for appropriate treatment without any delay.
Skin sensitivity: Pathergy is a condition signifying sensitivity of the skin, particularly injury or irritation. Even a needle prick can lead to developing a large red lump in a day or two.
Gastrointestinal symptoms: Inflammation of the stomach and intestines causes symptoms such as loss of appetite, stomach pain, indigestion, diarrhea, feeling sick and vomiting. There is a possibility of damage to the bowel resulting in bleeding. Blood in stools suggests inflammation of the internal lining of the bowel.
Blood clots: Inflammation of the veins can lead to formation of blood clots or thrombosis.
Joint pain: Joint pain in ankles, wrists, knees, elbows and hips is common. Inflammation in the joint can cause swelling, redness and tenderness.
Brain: Meninges is the coverage of the brain. Inflammation of the brain or tissue that covers the brain (meninges) causes symptoms like headache, neck stiffness along with high body temperature. In severe cases, it can damage the nervous tissue and lead to extreme weakness or impaired function of the body.
Aneurysms: Aneurysms are outpouchings of blood vessel walls due to inflammation of arteries in the lungs. This can lead to massive lung hemorrhage. Symptoms include pain in the limbs, severe headache, feeling dizzy, and breathlessness, coughing up blood, confusion and loss of consciousness.
Inflammation of the nervous system: Inflammation of the central nervous system occurs in 5%-10% of reported cases. This is regarded as the most serious symptom. Typical symptoms include headache, double vision, loss of balance, seizures, partial paralysis on one side of the body, personality changes. Any of these are noticeable within the first five years of recognizing initial symptoms.
General symptoms: Experiencing extreme fatigue to the extent that it interrupts with everyday routine is a general symptom of Behcet's syndrome.
Behcet's Syndrome Causes
The exact cause remains unclear. Though regarded as an autoimmune disorder, it is unclear what triggers the autoimmune disorder. Other possible association is genetics. Certain ethnic groups or a family member with the disease increases chances of developing Behcet's syndrome. People with gene HLA B51, variations in other genes like IL10, IL23R-IL2RB2 increases the risk of developing the disease considerably. However, the condition does not have a clear pattern of incidence.
Risk factors identified include:
Age: Children and older adults can develop the condition. But men and women in the age group of 20-3 are more likely to be affected.
Location: People from countries in the Middle East and Far East, including Turkey, Iran, Japan and China are more likely to develop Behcet's syndrome.
Sex: The disease is more severe in men.
Genes: Having certain genes increases the risk of developing the syndrome.
Behcet's Syndrome Diagnosis
In the absence of a single test to diagnose Behcet's syndrome, doctors look out for symptoms. Blood tests or other laboratory tests are recommended to rule out other disease or illness. The criteria include:
Mouth sores: Mouth sores are very common. Many disorders are related to mouth sores. If the mouth sores recur every three months in 12 months, it is regarded as criteria for evaluating the disease.
Doctors look for two additional signs.
Behcet's Syndrome - time to seek help
Recognizing symptoms and relating the symptoms to Behcet's disease is essential. Note down symptoms being experienced and add related information that affects normal routine. Seek appointment with a doctor. If medical attention is delayed, the condition can worsen and lead to losing eye sight or a stroke. At the meeting, divulge family history and inform about medications for any other health issue or supplements being taken.
You are most likely to seek specialist help. Rheumatologist for arthritis, joint pain etc, Ophthalmologist for eye problems, gynecologist or an urologist for genital sores, dermatologist for skin issues, Gastroenterologist for digestive difficulties or neurologist for symptoms related to CNS (central nervous system).
Behcet's Syndrome Treatment
There is no cure for Behcet's syndrome. The treatment is aimed at alleviating the symptoms, reducing the frequency and intensity, put the disease into remission and prevent serious complications. Medicines for controlling the individual symptoms are prescribed. Some medicines are prescribed with other medicines to suppress the activity of immune system. Some medicines can have side effects too.
For the skin: gels, creams and ointment that contain a Corticosteroid to reduce the inflammation.
For mouth sores: Special mouth washes with Corticosteroid to reduce the pain and associated discomfort.
For the eyes: Eye drops with Corticosteroid to relieve pain and redness in the eye.
Coping with Behcet's syndrome
Painful, stiff joints are the primary symptoms of rheumatoid arthritis. Rheumatoid arthritis is an autoimmune disease resulting in chronic inflammation of the joints. More than one joint is usually affected. Women are more predisposed to contracting rheumatoid arthritis. It usually sets in when a person is between 40 - 60 years. The exact reason for the autoimmune system attack is not known. This condition is hereditary and can be brought about by environmental and hormonal factors. Tissues around the joint become inflamed in a rheumatoid arthritic condition. During an attack of rheumatoid arthritis, symptoms such as fatigue, lack of appetite, low grade fever and joint stiffness are noticed. The symptoms are most notable in the morning or after long periods of inactivity. These attacks come and go.
Rheumatoid arthritis is a progressive disease that can lead to joint destruction and functional disability. Multiple joints including small joints of the hands and wrist are often affected. Rheumatoid arthritis can be extremely debilitating, thereby making simple chores painful. In fact, rheumatoid arthritis can even affect the salivary glands, tear glands and heart and lungs.
A rheumatologist will diagnose the condition based on blood test, x-rays and physical examination. The joints are examined for inflammation and deformity and presence of rheumatoid nodules. In persons suffering from rheumatoid arthritis, blood antibodies such as citrulline are noticed. Arthrocentesis or extraction of joint fluid is also conducted. There is no known cure for rheumatoid arthritis. Medication is prescribed to relieve joint inflammation and prevention deformation of the joints. First-line drugs like corticosteroids or aspirin are used to reduce pain and inflammation whereas second-line drugs such as methotrexate and hydroxychloroquine are prescribed for preventing progressive joint destruction. An exercise regimen may need to be followed for preventing work disability and strengthening the joints.
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Diseases, Symptoms, Tests and Treatment arranged in alphabetical order:
Bibliography / Reference
Collection of Pages - Last revised Date: April 23, 2019