CK blood test
A Creatinine Kinase test is a blood test that measures the levels of Creatinine phosphokinase (CPK). It is an enzyme found predominantly in the heart tissue, brain and skeletal muscle. The CK blood test is commonly used to diagnose the existence of heart muscle damage. The CK blood test result shows an increase above normal in a person's blood test about six hours after the start of a heart attack.
It reaches its peak in about 18 hours and returns to normal in 24 to 36 hours. When the total CPK level is substantially elevated, then it is indicative of injury or stress to heart, brain or skeletal areas. The small amount of CPK that is normally in the blood comes from the muscles. The CPK blood test also helps in cost-effective management of people with suspected coronary atherosclerosis. It also evaluates the extent of muscle damage caused by drugs, trauma or immobility.
Abnormal CK-MB (one of three CK isoenzymes) or troponin levels are associated with Myocyte Necrosis and the diagnosis of Myocardial infarction. The Cardiac Markers of Cardiac Myocyte Necrosis (damage to the Cardiac muscle cells), myoglobin, CK, CK-MB and troponin I and T are primarily used to identify acute Myocardial Infarction.
It is used in early detection of dermatomyositis and polymyositis. It is also used to distinguish malignant hyperthermia from a post operative infection. It helps to discover carriers of muscular dystrophy.
The normal range for Creatinine Kinase (CK or CPK) blood test:
Male: 38 - 174 units/L
Female: 96 - 140 units/L
Increased levels of CK also can be found in viral myositis and hypothyroidism. Higher than normal CPK levels is indicative of the following conditions:
Serum CKMB levels are tested to check for myocardial injury. It is another important cardiac marker. The primary source of CKMB is myocardium although it is also found in skeletal muscle. Typically CKMB tests have now been replaced by Troponin test. But in cases of abnormal Troponin assay results or suspected re-infarction in the hospital, the CKMB serum test is still used.
High levels of CK MB are noticed in cases of polymyositis and rhabdomyolysis. Patients suffering pulmonary embolism, hypothyroidism, and muscular dystrophy or carbon monoxide poisoning can also show higher levels of serum CKMB. The reference range is about 56.2 pg/mL.
BUN blood test
Healthy kidneys filter urea nitrogen through the urine. The BUN blood test measures the urea nitrogen levels in your blood as an indicator of the efficiency of the kidneys. BUN - Blood Urea Nitrogen blood test indicates the functioning of the kidneys. The BUN concentration is measured by analysis of serum or plasma. It is also done to check for efficiency of dialysis. BUN blood test measures the levels of urea nitrogen in the blood. BUN blood test results can be compared with creatinine test to check for dehydration. BUN - creatinine ratio can throw light on kidney functioning.
BUN blood test levels
Normal BUN blood levels are 7 - 20 mg/dl. Abnormal levels of BUN are usually indicative of renal failure or bleeding into the stomach or intestines. High levels of BUN in the blood can mean congestive heart failure, gastrointestinal bleeding, urinary tract obstruction or myocardial infarction. BUN blood levels are noticed to be higher in diabetics. This is due to accumulated stress on the kidneys over years. This leads to kidney failure and dysfunction. Acute dehydration raised BUN blood levels due to inadequate level of fluids in the body. Lower levels of BUN in the blood may suggest malnutrition or liver failure. Some women notice decrease in BUN level in the third trimester of pregnancy.
CMP blood test
A CMP (Comprehensive Metabolic Panel) blood test is a set of specific tests that aid in providing a physician with vital information on the status of a patient's liver, kidneys, blood sugar, blood proteins and electrolyte balance. Often a CMP blood test is part of a yearly examination. The CMP blood test encompasses:
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Bibliography / Reference
Collection of Pages - Last revised Date: December 4, 2023