Lung cancer has been commonly associated with cigarette smoking and use of tobacco. Lung cancer can surface in any part of the lung, though most instances of lung cancer are noticed in the epithelial lining. Smoking is the cause for nearly 90%of the cases of lung cancer. Tobacco smoke contains carcinogens that contribute towards the development of lung cancer. Women smokers are at greater risk of lung cancer than men smokers. Even passive smoking is fraught with risks. Another cause for lung cancer is exposure to asbestos fibers. This gives rise to mesothelioma. A small percentage of lung cancer cases are attributed to radon gas exposure. Persons suffering from COPD (chronic obstructive pulmonary disease) at at increased risk for lung cancer. Air pollution arising from vehicular and industrial effluents can increase the risk of lung cancer.
Symptoms of lung cancer include coughing and wheezing and chest pain. A patient suffering from lung cancer may notice blood while coughing. There might be extreme fatigue and unexplained weight loss. Lung cancer patients are more likely to face repeated respiratory infections such as bronchitis and pneumonia. Other symptoms of lung cancer include difficulty in swallowing and enlargement of lymph nodes on the neck.
The physician will look into the lungs with a bronchoscope. Tissue samples are often taken for biopsy. Sputum cytology is also conducted to detect presence of lung cancer cells. Chest x-ray and examination is done. Tissue biopsy of lymph nodes is done to diagnose lung cancer. Chemotherapy and radiotherapy are used in the treatment of lung cancer.
Nicotine Blood Test
A nicotine blood test measures the rate of metabolization of nicotine. This gives an indication of the possible success of using nicotine patches to tackle craving while a person is giving up smoking. Cotinine is the substance that nicotine metabolizes into before turning into 3-hydroxycotinine. If a nicotine blood test indicates a rapid metabolism of nicotine, the person is likely to experience more craving while trying to give up smoking. Nicotine tests can also be performed on urine or saliva.
Cold burn or Frostbite occurs when the skin is in touch with an extremely cold body. Extreme cold can cause damage to the skin and underlying tissues. For example, if there is a prolonged contact of the skin with moderately cold body like snow or very cold bodies like dry ice, liquid helium or liquid nitrogen for a brief period, cold burns or ice burns will occur. Here heat is transferred from the skin and organs to the cold body that is in contact. In other kinds of burns, the body that causes the burn is hotter and heat is transferred to the skin or the organ.
Symptoms of frostbite include pins and needles sensation and then numbness in the area. Initially there may be throbbing or aching. The affected part seems to become insensate. In severe frostbite, when the tissue starts to freeze, the skin at that area may appear white and numb. In areas affected by frost burn, abnormal accumulation of blood takes place. In addition to accumulation of body fluids, a blood clot may form thereby preventing blood circulation around the area resulting in tissue decay. Mottled and violaceous tissue is noticed. Normal functioning of the body is disturbed because of cooling of the internal organs, which will lead to a critical condition called hypothermia. Cooling of the brain or heart is very dangerous.
If hypothermia is noticed, treating it should be the priority. Blisters are noticed when there is very severe frostbite. Blisters are the result of expansion of the surrounding layers of the skin and the release of serous fluid or plasma.
The accumulated plasma in the blister is intended to prevent further damage and also to help in the healing process. To avoid infection from the blister, it is important that it is not punctured as it would expose the raw skin for further infection. The serous fluid will be reabsorbed by the skin usually after 24 hours if there is no infection.
Severe frostbite may also damage tendons, muscles, nerves and bones. Gangrene is inevitable in the case of very severe frostbite. Frostbite may affect any part of the body.
The most vulnerable parts are hands, feet, nose and ears. Recovery may be significant when the skin and underlying body tissues are injured and it may be permanent if there is injury to the blood vessels. If gangrene follows, the affected part may have to be amputated. When warming up of the affected part begins, the patient will experience intense pain. There will be tingling or burning sensation in the affected area also.
People taking beta-blockers that decrease blood flow to the skin and those who suffer Peripheral Vascular Disease are at risk when exposed to cold for a prolonged period. Any person who is exposed to extreme cold for a long period is susceptible to frostbite. Diabetes, peripheral neuropathy or Raynaud's phenomenon are some conditions that may have increased risk of cold burns. Smoking and windy weather when the rate of heat loss from the skin is more will hinder the healing process. Cold burns at the work place are common. People who work in factories where they may come in contact with metal surfaces that are at extremely cold temperatures are prone to cold burns. When the skin is moist, they may receive almost instantaneous cold burns.
Prevention of freeze burns
Extreme cold, wet clothes, high winds and poor circulation are some of the factors that can contribute to freeze burns. Tight boots or clothing and conditions like cramped positions, some medications, smoking or alcohol can cause frostbite. Wearing appropriate clothing in winter when the temperature goes below normal and will help. Winter clothes like mittens, layered clothing that is wind-proof and water resistant gives good protection.
First Aid for cold burns
It is essential that the ice burn treatment is correctly done as soon as possible.
Frostnip is the least severe form of cold injury that occurs after the distal extremities are exposed to prolonged period of cold but non-freezing temperatures. Vasoconstriction is felt. Frostnip is a precursor to frostbite and does not involve the same levels of tissue destruction. The affected area appears pale.
Immersion foot is a condition where there is severe tissue injury due to prolonged and persistent exposure to wet conditions, cold or hot. It results in tissue edema and inflammation. This is often seen in homeless persons who are exposed to the elements. The extremities appear swollen and erythematous (skin turning red often manifested in patches). Bad odor is often noticed as also tissue sloughing.
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Bibliography / Reference
Collection of Pages - Last revised Date: January 29, 2020