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Klinfeller Syndrome

The predominant cause of Klinfeller syndrome is the chromosomal mosaic which creates an additional X chromosome that affects the growth and development of the reproductive organs. It occurs mostly in men. One of the characteristic features of Klinfeller is decreased testicular size and poor spermatogenesis (production of spermatozoa). Identification tests such as semen analysis, bone density are done in order to decide the mode of treatment. Cell Karyotyping is also performed to identify chromosomal abnormalities. Reduced testosterone levels may lead to gynecomastia and in some cases even mastectomy is advised as a treatment option. Other treatment options include the testosterone replacement therapy.

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Collection of Pages - Last revised Date: October 20, 2020