Afibrinogenemia

Afibrinogenemia is an inherited blood disorder that is caused due to a recessive gene. Congenital Afibrinogenemia is caused due to deficiency of fibrinogen protein that is essential for blood clotting. Afibrinogenemia is tested by checking for PT (Prothrombin time), blood clotting time, fibrinogen level and bleeding time.

Symptoms of afibrinogenemia include abnormal bleeding in Gastrointestinal tract, nose, joints and bruises. Intracranial bleeding (bleeding in the brain) is a situation that can be fatal to the patient. A person suffering from Afibrinogenemia can be given blood plasma before any surgery or to treat excessive bleeding situations. Care should be taken to ensure that the patient is vaccinated against Hepatitis B. Such patients are likely to from blood clots (thrombosis).