Folate or Vitamin B9 is folic acid or folacin, that helps to produce red blood cells and it essential for DNA creation. Dried beans, legumes, green leafy vegetables, orange juice, asparagus, fortified bread, rice, and cereals are all good natural sources of Vitamin B9.
RDA - Recommended Daily Allowance:
Adults - Men: 400 mcg
Adults - Women: 400 mcg
Pregnant Women: 600 mcg
Breast feeding Women: 500 mcg
Vitamin B9 is generally well tolerated but may mask a Vitamin B12 deficiency with high doses. Deficiency of Folate can result in Megaloblastic Anemia which is also known as large cell Anemia or Macrocytic Anemia. Deficiency during the time of pregnancy or the period preceding pregnancy may result in neural tube defects in the fetus.
Weakness, loss of strength or lack of energy is described as Asthenia. This weakness results in reduced strength thus making it difficult for a person to perform or complete a task. This condition may be indicative of a larger problem/disease. Asthenia is experienced differently by different people thus making it difficult to understand the underlying problem.
The entire body may be affected or only a part of the body may be affected. Asthenia can affect people belonging to any age group. A person suffering from asthenia may not be in a position to complete any task. Asthenia as a condition may be continuos, chronic or temporary. It is more a symptom than a condition itself. It is not life threatening; but it does affect the quality of life. The weakness experienced can either be perceived or true.
Weakness is classified as true weakness when there is an actual loss in muscle strength and capability that may have been caused due to an injury or muscle defect. Weakness is termed as perceived weakness when the muscles of a person are functioning well and yet he feels unable to complete the task. This type of weakness is non-neuromuscular weakness.
Symptoms may vary depending on how much of the body is affected; part of the body or the entire body. The symptoms also vary depending on the underlying condition and other symptoms that exist. When the entire body is affected, the symptoms include:
When only part of the body is affected, the symptoms include slow movement, muscle twitching and muscle cramps. If asthenia is present along with other symptoms like extreme pain, slurred speech, confusion, change in vision etc, it needs immediate medical attention.
Common causes for asthenia include:
Sedentary lifestyle: Leads to muscle waste, muscle fibers are replaced by fat due to inactivity thereby reducing muscle fitness.
Advancing age: With age, the muscles in the body loosen or weaken.
Infection: Infection leads to muscle inflammation thus making it weak.
Chronic diseases: Chronic diseases may reduce blood and nutrient supply to muscles thus making them weak.
Vitamin deficiency; in particular vitamin B9
Anxiety or depression
Adverse effects of certain medicines
Treatment for other diseases like radiation therapy or chemotherapy
Chronic lung disease
Asthenia classified as per cause
Asthenia can be classified based on what causes the condition. Common types include:
The underlying cause of asthenia determines the treatment. Based on what has caused asthenia, treatment is prescribed.
Vitamin B complex
B Vitamins - the group of water soluble vitamins essential for the normal functioning are not usually produced by our bodies and require to be replenished regularly.
Vitamin B1 - Thiamine
Vitamin B2 - Riboflavin
Vitamin B3 - Niacin, Niacinamide
Vitamin B5 - Pantothenic acid
Vitamin B6 - Pyridoxine
Vitamin B7 - Biotin
Vitamin B9 - Folic Acid
Vitamin B12 - Cyanocobalamin
Some Vitamin B Complex formulations, in addition to the above major B Vitamins, may contain inositol, choline bitartrate and Para Amino Benzoic Acid - PABA.
Vitamin B5 also known as Pantothenic acid is often used in combination with other B Vitamins in Vitamin B formulations. Vitamin B5 is primarily used for treating dietary deficiencies, acne, alcoholism, allergies, baldness, asthma, attention deficit-hyperactivity disorder (ADHD), autism, burning feet syndrome, yeast infections, heart failure, carpal tunnel syndrome, respiratory disorders, celiac disease, colitis, conjunctivitis, convulsions and cystitis. Some times Vitamin B5 is also used for controlling dandruff, depression,tongue infections, gray hair, headache, hyperactivity, low blood sugar, insomnia, irritability, muscular dystrophy, muscular cramps in the legs associated with pregnancy or alcoholism and improving athletic performance.
RDA - Recommended Daily Allowance:
Adults - Men: 5 mg
Adults - Women: 5 mg
Pregnant Women: 6 mg
Breastfeeding Women: 7 mg
Vitamin B5 is generally well tolerated in moderate doses but may produce adverse side effects like diarrhea with high doses.
Biotin or Vitamin B7: RDA - Recommended Daily Allowance:
Adults: 30 microgram
Biotin deficiency manifests in the form of scaly inflammation of the skin, poor appetite, nausea, vomiting, anemia, depression and general weakness.
Bibliography / Reference
Collection of Pages - Last revised Date: February 16, 2019