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Stevens Johnson Syndrome

Stevens Johnson Syndrome or SJS is a potentially deadly skin condition with symptoms similar to erythema multiforme but in a much more severe and extensive manner.

SJS, depending upon the severity is also known as Toxic Epidermal Necrolysis (TEN) - a violent reaction that comes after exposure to some drugs like allopurinol, sulfonamide antibiotics, lamotrigine, carbamazepine, nevirapine and phenytoin.

SJS can affect any age group, particularly older people. It can be caused by a drug hypersensitivity. A patient with impaired immune system like HIV, or one who is undergoing radiation therapy has higher chances of SJS. Stevens Johnson syndrome symptoms include flu-like symptoms in addition to the rashes. There is blistering on the skin and mucus membranes. Infection that enters through the blistered and affected areas can be deadly and life-threatening. The patient may develop red eyes and joint pains. The skin lesions are often referred to as target lesions since they are characterized by concentric rings of red, white and red. Conjunctivitis is sometimes noticed. Treatment for Stevens-Johnson syndrome include topical anesthetics, corticosteroids and antibiotics. Usually the patients suffering from this condition are hospitalized. It may take a few weeks for a patient to recover from SJS.

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Collection of Pages - Last revised Date: November 22, 2019