Bullous Pemphigoid is a very rare skin condition that gives rise to large, fluid-filled blisters. These blisters develop in the area of the skin that can flex, e.g. the armpits, lower abdomen and upper thighs. It can appear in a few areas in the body or can be widespread. One third of the patients develop blisters in their mouth, throat and esophagus apart from the skin. The condition occurs when the body's immune system attacks a thin layer of the tissue below the outer layer of the skin.
Bullous Pemphigoid is a rare occurrence in young adults and children. This condition is common in older people within the age group of 50 to 80. Bullous Pemphigoid is also slightly more common in women than men. Bullous Pemphigoid can get life threatening for older people with poor health. The condition settles down on its own within 5 years. In a few extreme cases, the condition lasts longer. The condition is not infectious and does not spread. Bullous Pemphigoid is commonly seen in the areas of the arms, mouth, groin, legs and abdomen. The exact cause for Bullous Pemphigoid is not clearly known. It is an autoimmune disease.
If the blisters are concentrated around the mucous membranes of your eyes and mouth, then it is called mucous membrane pemphigoid. Blisters on the eyes can lead to scarring.
Skin biopsy is done. A blood test may help detect pemphigoid antibodies. This can be detected from urine sample of the person or from the fluid collected in the blister. The common treatment involved in treating Bullous Pemphigoid is aimed at relieving the person from itching and to heal the affected skin. Treatment may include corticosteroids, drugs to fight inflammation and drugs to suppress the immune system.
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Collection of Pages - Last revised Date: February 23, 2024