Insulin Reaction
Insulin is used to lower high levels of blood sugar. Insulin treatment is given to diabetics either as an oral hypoglycemic agent or through an injection. In some cases, insulin reaction is noticed, especially among those suffering from severe diabetes. Insulin reactions can range from hunger pangs and sweating and trembling to dizziness, abnormal behavior and unconsciousness. A person can even suffer a stroke. Hypoglycaemia is a common reaction to insulin. This can happen due to increased activity or late/missed meals. An increase in the insulin dosage can also bring about such a reaction. When there is malfunctioning in the kidneys or thyroid, an insulin reaction may be noticed.
A reaction to the insulin occurs soon after the insulin in injected. The reduced blood sugar level brings on hypoglycaemia and its consequent reactions. If you notice such an insulin reaction, notify your doctor immediately. Eating something immediately will help alleviate the symptoms. Consume juice or candies if you notice symptoms of insulin reaction. A few ounces of milk or wholegrain crackers will also help. When a person loses consciousness due to an insulin reaction, he is usually given an injection of glucagon - a prescription drug that elevates blood sugar levels. It is advisable for insulin-dependent diabetics to carry hard candy, sugar cubes or cheese crackers with them at all times for such a situation.
Insulin resistance
Insulin resistance or Metabolic syndrome is a condition where the body's insulin is not properly utilized. This condition also called Syndrome X is often called impaired fasting glucose (IFG) or Pre-diabetes. In an attempt to compensate the insulin resistance, the body produces extra insulin that leads directly or indirectly to the metabolic abnormalities.
Causes for Syndrome X
Obesity metabolic syndrome: A large waistline or abdominal obesity, which generally is 40 inches or more for men and 35 inches or more for women.
Physical inactivity: Metabolic syndrome is associated with sedentary lifestyles like adipose tissue, reduced HDL cholesterol, increased triglycerides (fat found in blood), blood pressure and glucose in the genetically susceptible.
Aging: The prevalence of metabolic syndrome increases with age.
Diabetes Mellitus: Metabolic syndrome is found in large majority of patients with Type-2 diabetes or impaired glucose tolerance (IGT).
Coronary Heart Disease: Patients with coronary heart disease are at higher risk of developing metabolic syndrome.
Tackling Metabolic Resistance
Physical activity for at least 30 to 60 minutes a day is generally recommended. Losing weight is imperative to dealing with metabolic syndrome. Follow a healthy diet. Insulin resistance is increased by smoking cigarettes. part from weight loss and exercise, few drugs are also prescribed to reduce the LDL cholesterol levels. Drugs prescribed for this kind of treatment include statin, a fibrate drug or a combination of a statin with either niacin or a fibrate.
Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a life-threatening condition when the body has practically no insulin. This insulin deficiency results in extremely high blood sugar levels. Consequently, the muscle, fat and liver cells cannot use glucose for fuel. These cells are converted into glucose by hormones such as glucagon and adrenalin and turned into ketones through oxidation. As a result, the body uses fat for fuel. The increased levels of blood sugar are not flushed through urination. DKA is usually noticed in patients suffering from Insulin-dependent diabetes. A person can suffer from diabetic ketoacidosis if there has been severe dehydration and consequently the blood chemistry has been affected. There is accumulation of organic acids and ketones in the blood. Elevated ketone levels in the body upset its blood pH and make the blood acidic thereby triggering a toxic condition for the body's cells. Diabetic ketoacidosis is noticed when hyperglycemia exceeds over 300 mg/dL. If diabetes ketoacidosis is not attended in time, it can lead to coma and death. Surgery, infection, trauma, stroke or heart attack can also trigger diabetes ketoacidosis. Insufficient fluid intake, pancreatitis and alcohol abuse can trigger diabetes ketoacidosis.
Symptoms of diabetes ketoacidosis include excessive thirst and general weakness. There is frequent urination, loss of appetite and vomiting. Other symptoms of diabetes ketoacidosis are weight loss and abdominal pain. A person suffering from DKA tends to experience low blood pressure and increased heart rate. High ketone levels can give rise to a fruity-scent on the breath and vomiting. The patient will be restless and agitated. The skin will be hot and dry and appear flushed. Patients suffering from diabetes must check their blood glucose levels if they notice any symptoms of diabetes ketoacidosis. Poor diabetes management can lead to DKA.
Acidosis can be checked by testing the pH of the blood. Normal blood pH ranges from 7.35 to 7.45. If it is observed to be below 7.35, acidosis may have set in. Ketosis, acidosis and hyperglycemia can be diagnosed through blood tests. The patient will need fluid replacement till the body is sufficienty rehydrated. Electrolytes must also be suitably replaced as they are essential to the working of major organs and nerve cells. Electrolyte imbalance can lead to severe health hazards. Intravenous insulin aids in using up glucose for energy. Thus the breakdown of fat is stopped. Consequently acidosis and ketosis processes will be reversed.
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