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Lymphogranuloma Venereum

Lymphogranuloma Venereum or LGV is caused by the Chlamydia trachomatis bacteria. This is caused most often by sexual contact but it can also occur due to other reasons. Lymphogranuloma Venereum is a sexually transmitted disease (STD) that is more prevalent in the tropical areas. Lymphogranuloma Venereum affects the lymph nodes and causes scarring and destruction of tissue. In the initial stage, Lymphogranuloma Venereum remains as a painless blister. When the disease lasts for a few months, it can spread to the lymph nodes. This may lead to lymphatic obstruction, chronic edema and fibrosis. Left untreated, it can lead to Genital elephantiasis.


Lymphogranuloma Venereum manifests as a small painless ulcer on the male or female genitalia. Swelling and tenderness is experienced in the surrounding lymph nodes. A patient suffering from Lymphogranuloma Venereum may have fever and loss of appetite. There may be drainage from the inguinal lymph nodes and redness and swelling. Women might notice abdominal pain and fistulas.


Multiple sexual partners is a leading cause for Lymphogranuloma Venereum. A blood test can confirm lymphogranuloma venereum based on antibodies against Chlamydia trachomatis. Biopsy of the lymph node or serology test for LGV are also conducted to help diagnose the condition. Antibiotic therapy can cure Lymphogranuloma venereum. Medications such as Tetracycline, Doxycycline, Erythromycin are prescribed.

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Collection of Pages - Last revised Date: October 18, 2017