Migraine
Nearly everyone gets headaches. But while some are tension headaches or headaches caused by a cold. Migraine headaches tend to rather severe. Migraine headaches tend to be severe and recurrent and are often accompanied by nausea. What begins as a pain on one side of the head may spread to both sides. Most migraine headaches are caused by a change in the blood flow pattern to the brain.
Triggered by stress or other factors, arteries supplying blood to the brain may constrict. Serotonin, a chemical may also have a role to play since it is released from nerve fibers that coil around the blood vessels. To tackle this, certain arteries within the brain may dilate to accommodate better oxygen supply. This dilation may result in migraine headaches. While anyone can get migraine headaches, they are more common in women.
Causes of migraine
Often changes in weather or altitude can cause migraine headaches. If you have irregular sleeping patterns (too much or too little), it may be the cause for migraine headaches. An interruption of your regular sleep pattern may bring on a headache. Strong odors, bright lights and loud noises are known to be triggers for a migraine attack. Fasting is yet another triggering factor for migraine headache. Women may experience migraine headaches on account of their menstrual cycle, birth control pills or hormones. Women who are on oral contraceptive pills are more likely to develop migraine headaches as a side effect.
Symptoms of Migraine
- Throbbing pain on one or both sides of the head
- Nausea and vomiting
- Stiff neck
- Sensitivity to light and sound
- Visual hallucinations such as zigzag lines and flashing lights
- Tiredness, irritability and confusion
- Mood swings
- Sensitivity to cold
- Diarrhea and increased urination
Treating Migraine
Medication to treat migraines can range from ergots like ergotamine or triptans like sumatriptan and rizatriptan. Sometimes isometheptenes are also prescribed. Ergotamines narrow the blood vessels to reduce the throbbing pain. Triptans perform the dual function of narrowing the blood vessels as well as balancing the chemicals in the brain. Eat a healthy diet and keep your weight under check. Obese people are more likely to suffer migraine headaches. Smoking and excessive alcohol consumption can bring on severe migraines.
Tension Headache
Do you feel a dull ache on both sides of the head? Do the muscles in the neck and head feel tight and? You are most likely suffering a tension headache or stress headache as it is otherwise referred to. Such headaches are one of the most common forms of headache and can occur in adults and adolescents. The pain due to tension headache is wise-like and is generalized. Tension headaches may result from fluctuations in the levels of brain chemicals such as serotonin, endorphins and others. Tension headaches are noticed more often in women.
Tension headaches occur due to contraction of neck and scalp muscles. This contraction can be a reaction to stress, anxiety or posture. Excessive smoking, alcohol use, sinusitiss, eye strain can also bring on tension headache. Unlike migraine, tension headaches do not cause nausea and vomitting or numbness. Episodic tension headaches come a couple of times a month and last a few hours. If there are frequent episodes of tension headache, the condition is chronic. Skipping meals, stress, hormonal changes and hypertension medication can trigger tension headaches. Such headaches often have a genetic predisposition.
Tension headaches are treated with NSAIDs, aspirin or acetaminophen. A nonsedating muscle relaxant such as Skelaxin provides relief to persons suffering from tension headaches. Those who suffer from frequent bouts of tension headaches may need medications to reduce anxiety such as amitriptyline, nortriptyline or desipramine. But overuse of these medicines can lead to rebound headaches. You can try some of the following measures to bring tension headaches under control:
- Enough rest
- Regular exercise regimen
- Warm or cold compress on the head and neck
- Relaxation exercises, yoga, deep breathing, acupuncture
- Good posture while sleeping, reading, using the computer
- Massage
- Swimming
Sumatriptan
Sumatriptan, part of the family of drugs called as triptans is prescribed for the treatment of Migraine and cluster headaches. Migraine headaches are thought to be the result of dilation of blood vessels in the head. Sumatriptan causes constriction of the blood vessels thus relieving Migraine. Triptans are technically abortive migraine medications. However, Sumatriptan does not prevent or reduce the number of migraine attacks. There is another 'triptan' drug which has slightly less side effects than Sumatriptan - Rizatriptan.
Dosage and Administration: Starting dosage may be 25 mg or at the discretion of the physician. However, the Physician might want the patient to take the first dosage at his office to monitor any adverse heart events. Normal dosage is 25 mg to 100 mg or as prescribed by the Physician. Maximum dose in any 24 hours should not exceed 300 mg orally. Do not use Sumatriptan concomitantly with Ergotamine containing preparations.
Safety and efficacy has not been proved for patients over 65 years or for children.
Contraindications: The use of Sumatriptan is contraindicated in hypersensitivity, ischemic heart disease or previous myocardial infraction, Prinzmetal's angina, coronary vasospasm and controlled hyper tension. Sumatriptan should not be used unless there is a clear diagnosis of Migraine. Before use, exclude underlying cardiac disease especially in patients with risk factors. Chest symptoms may occur which mimic angina but are rarely found to be the result of vasospasm. Vasospasm may result in arrhythmia, ischemia or myocardial infarction. This drug is to be avoided for patients with impaired renal or hepatic functions.
Sumatriptan should not be administered along with ergot type migraine medications, or with MAO inhibitors. Sumatriptan and Ergotamine together can cause prolonged spasm of the blood vessels. It is essential that the use of these two medications should be separated by at least 24 hours.
Side Effects of Sumatriptan: Pain, tingling sensation, heaviness or pressure in the chest region which may be transient. Rarely severe flushing, dizziness, paresthesia, weakness, fatigue, drowsiness may occur. Transient rise in blood pressure may occur.
Bibliography / Reference
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